Lennart Mucke Selected Research

Calbindins

11/2015	Network dysfunction in α-synuclein transgenic mice and human Lewy body dementia.
1/2011	Quantifying biomarkers of cognitive dysfunction and neuronal network hyperexcitability in mouse models of Alzheimer's disease: depletion of calcium-dependent proteins and inhibitory hippocampal remodeling.
10/2005	Vulnerability of dentate granule cells to disruption of arc expression in human amyloid precursor protein transgenic mice.
10/2005	Fyn kinase induces synaptic and cognitive impairments in a transgenic mouse model of Alzheimer's disease.

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Lennart Mucke Research Topics

Disease

55	Alzheimer Disease (Alzheimer's Disease) 11/2021 - 06/2002
15	Cognitive Dysfunction 01/2019 - 06/2002
9	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2018 - 08/2002
8	Amyloid Plaque 01/2020 - 03/2004
7	Epilepsy (Aura) 01/2022 - 09/2013
7	Memory Disorders (Memory Loss) 01/2018 - 06/2002
3	Autistic Disorder (Autism) 01/2022 - 01/2020
3	Brain Diseases (Brain Disorder) 01/2022 - 01/2021
3	Inflammation (Inflammations) 11/2018 - 08/2002
3	Dementia (Dementias) 11/2015 - 05/2006
3	Seizures (Absence Seizure) 11/2015 - 04/2009
3	AIDS-Related Complex (ARC) 01/2011 - 10/2005
2	Myoclonic Epilepsies (Myoclonic Encephalopathy) 01/2022 - 09/2014
2	Neuroinflammatory Diseases 01/2019 - 11/2018
2	Nervous System Diseases (Neurological Disorders) 01/2018 - 10/2016
2	Parkinson Disease (Parkinson's Disease) 01/2018 - 01/2011
1	Megalencephaly 01/2022
1	Sudden Unexpected Death in Epilepsy 01/2022
1	Multiple Sclerosis 11/2018
1	Schizophrenia (Dementia Praecox) 01/2018
1	Autism Spectrum Disorder 01/2018
1	Intellectual Disability (Idiocy) 01/2018
1	Tourette Syndrome (Tourette's Syndrome) 01/2018
1	Lewy Body Disease (Lewy Body Dementia) 11/2015
1	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 10/2014
1	Brain Concussion (Cerebral Concussion) 01/2014
1	Prion Diseases (Transmissible Spongiform Encephalopathies) 07/2008
1	Conversion Disorder (Astasia Abasia) 07/2008
1	Gliosis 05/2006
1	Mitochondrial Diseases (Mitochondrial Disease) 05/2006

Drug/Important Bio-Agent (IBA)

24	Amyloid (Amyloid Fibrils)IBA 01/2019 - 08/2003
24	Proteins (Proteins, Gene)FDA Link 01/2018 - 08/2002
18	Amyloid beta-PeptidesIBA 07/2010 - 08/2003
17	Peptides (Polypeptides)IBA 01/2016 - 11/2004
7	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 10/2016 - 05/2007
6	Apolipoprotein E4IBA 08/2010 - 06/2002
5	ApolipoproteinsIBA 03/2004 - 06/2002
4	tau Proteins (tau Protein)IBA 10/2021 - 01/2011
4	CalbindinsIBA 11/2015 - 10/2005
3	Levetiracetam (Keppra)FDA LinkGeneric 11/2021 - 10/2012
3	Prion ProteinsIBA 07/2011 - 07/2008
2	Flavin-Adenine Dinucleotide (FAD)IBA 01/2020 - 12/2004
2	DNA (Deoxyribonucleic Acid)IBA 01/2019 - 11/2015
2	Anticonvulsants (Antiepileptic Drugs)IBA 12/2016 - 04/2009
2	Phosphotransferases (Kinase)IBA 10/2016 - 10/2005
2	Voltage-Gated Sodium ChannelsIBA 09/2014 - 04/2012
2	N-Methylaspartate (NMDA)IBA 01/2011 - 10/2005
2	CalciumIBA 01/2011 - 08/2003
2	Phospholipases A2 (Phospholipase A2)IBA 08/2010 - 11/2008
2	Protein Isoforms (Isoforms)IBA 07/2008 - 12/2002
2	SirtuinsIBA 04/2008 - 12/2005
2	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 09/2005 - 12/2004
2	Apolipoproteins E (ApoE)IBA 03/2004 - 12/2002
2	Apolipoprotein E3IBA 12/2002 - 06/2002
1	Sirolimus (Rapamycin)FDA Link 01/2022
1	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2022
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 01/2020
1	TOR Serine-Threonine KinasesIBA 01/2020
1	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 01/2020
1	Fibrinogen (Factor I)FDA Link 01/2019
1	ChromatinIBA 01/2019
1	EpitopesIBA 11/2018
1	FibrinIBA 11/2018
1	Monoclonal AntibodiesIBA 11/2018
1	istradefyllineIBA 01/2018
1	Adenosine A2A Receptor (Adenosine A2A Receptors)IBA 01/2018
1	Indicators and Reagents (Reagents)IBA 12/2016
1	SynucleinsIBA 11/2015
1	Purinergic P1 Receptors (Adenosine Receptor)IBA 03/2015
1	ProgranulinsIBA 10/2014
1	Lamotrigine (Lamictal)FDA LinkGeneric 09/2013
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2011
1	Glutamate Receptors (Glutamate Receptor)IBA 01/2011
1	Neuropeptide YIBA 01/2011
1	Biomarkers (Surrogate Marker)IBA 01/2011
1	Essential Fatty AcidsIBA 08/2010
1	Arachidonic Acid (Vitamin F)IBA 08/2010
1	Aspartic Acid (Aspartate)FDA Link 01/2010
1	CaspasesIBA 01/2010
1	Presenilin-1IBA 04/2009
1	Presenilin-2IBA 04/2009
1	Neprilysin (Neutral Endopeptidase)IBA 02/2009
1	EnzymesIBA 02/2009
1	CollagenIBA 02/2009
1	Transforming Growth Factors (Transforming Growth Factor)IBA 02/2009
1	Fatty Acids (Saturated Fatty Acids)IBA 11/2008
1	PrionsIBA 07/2008
1	mu Opioid Receptors (mu Opioid Receptor)IBA 05/2008
1	EnkephalinsIBA 05/2008
1	beta-funaltrexamineIBA 05/2008
1	NeurotoxinsIBA 05/2007
1	Cathepsin BIBA 09/2006
1	thioflavin TIBA 09/2006
1	Cysteine Proteases (Cysteine Protease)IBA 09/2006
1	Endothelin-Converting EnzymesIBA 05/2006
1	IsoenzymesIBA 05/2006
1	Superoxide DismutaseIBA 05/2006
1	ResveratrolIBA 12/2005

Therapy/Procedure

2	Therapeutics 12/2016 - 03/2009
1	Immunotherapy 11/2018